江怀东

课题组长

江怀东，正教授 通讯地址：6号楼202D 电子邮件：jianghd@@shanghaitech.edu.cn  2003年毕业于山东大学晶体材料国家重点实验室，获材料学博士学位。2002年-2005年在新加坡国立大学物理系，任助理研究员、博士后研究员。2006年-2010年在美国加州大学洛杉矶分校物理与天文系，任博士后研究员、助理研究教授。2010年-2106年在山东大学任教授。2016年9月加入bat365中文官方网站，任教授。目前担任中国光学学会理事，主持国家重点研发计划“大科学装置前沿研究”重点专项、国家自然科学基金委重点项目等。

研究介绍

发表文章

Selected Publications

1. X. L. Li, N. Q. Gong, F. L. Tian, S. K. Zhang, Y. X. Zhang, Y. F. Wang, G. C. Qing, Y. C. Wang, F, Z. Li, Y. H. Xu, L. L. Zhang, J. J. Wang, Q. K. Ni, Y. L. Gan, C. J. Gu, H. D. Jiang, X. X. Huang, X. H. Shi, T. C. Zhang, Y. Wu, X. J. Liang, “Suppression of cytokine release syndrome during CAR-T-cell therapy via a subcutaneously injected interleukin-6-adsorbing hydrogel”, Nature Biomedical Engineering 7, 1129–1141 (2023).

2. Z. Dong^#, E. Zhang^#, Y. Jiang, Q. Zhang, A. Mayoral, H. Jiang^*, Y. Ma^*. “Atomic-level imaging of zeolite local structures using electron ptychography”, J. Am. Chem. Soc. 145, 6628-6632 (2023).

3. Z. Y. Du, Z. S. He, J. D. Fan, Y. G. Huo, B. He, Y. R. Wang, Q. Q. Sun, W. C. Niu, W. C. Zhao, L. N. Zhao, P. Cao, K. Cao, D. F. Xia, Q. Yuan, X. J. Liang, H. D. Jiang^*, Y. Gong^*, X. Y. Gao^*, “Au₄ cluster inhibits human thioredoxin reductase activity via specifically binding of Au to Cys189”, Nano Today 47, 101686 (2022).

4. J. Fan, Y. Tong, Y. Nie, Z. Gao, B. He, H. Luan, D. Lu, J. Zhang, D. Zhang, X. Yuan, J. Chen, Z. Guo, T. Liu, M. Zhang, C. Feng, H. Deng, B. Liu, Z. Zhao, Z. Liu, H. Jiang^*, “First commissioning results of the coherent scattering and imaging endstation at the Shanghai soft X-ray free-electron laser facility”, Nuclear Science and Techniques 33, 114 (2022). (Cover article)

5. A. Guo^#, J. Zhang^#, B. He, A. Li, T. Sun, W. Li, J. Wang, R. Tai, Y. liu, Z. Qian, J. Fan^*, A. Sali, R. Stevens, H. Jiang^*, “Quantitative, in situ visualization of intracellular insulin vesicles in pancreatic beta cells”, Proc Natl Acad Sci USA.119(32): e2202695119 (2022).

6. T. Li, B. He, X. Zhang, J. Fan^*, L. Gao, Z. Sun, J. Zhang, A. Guo, D. Pan, X. Yin, Y. Tong, C. Song, Y. Kohmura. M. Yabashi, T. Ishikawa, X. Gao^*, H. Jiang^*, “Three-Dimensional Quantitative Coherent Diffraction Imaging of Staphylococcus aureus Treated with Peptide-Mineralized Au-Cluster Probes”, Anal. Chem. 94, 13136-13144 (2022). (Supplementary cover article)

7. D. Pan, J. D. Fan^*, Z. Z. Nie, Z. B. Sun, J. H. Zhang, Y. J. Tong, B. He, C. Y. Song, Y. Kohmura, M. Yabashie, T. Ishikawae, Y. Q. Shen, H. D. Jiang^*, “Quantitative analysis of radiation effect on structure of mitochondria using coherent diffraction imaging with clustering algorithm”, IUCrJ 9, 223-230 (2022).

8. Z. S. He^#, F. Ye^#, C. Y. Zhang^#, J. D. Fan^#, Z. Y. Du, W. C. Zhao, Q. Yuan, W. C. Niu, F. P. Gao, B. He, P. Cao, L. N. Zhao, X. J. Gao, X. F. Gao, B. Sun, Y. H. Dong, J. C. Zhao, J. X. Qi, X. J. Liang, H. D. Jiang^*, Y. Gong^*, W. J. Tan^*, X. Y. Gao^*, “A comparison of Remdesivir versus gold cluster in COVID-19 animal model: A better therapeutic outcome of gold cluster”, Nano Today 44, 101468 (2022).

9. A. M. Guo, J. H. Zhang, Y. Wang, J. Fan, B. He, J. Wang, R. Z. Tai, X. J. Liang^*, H. D. Jiang^*, “Nanoscale detection of subcellular nanoparticles by X-ray diffraction imaging for precise quantitative analysis of whole cancer cells”, Anal. Chem.93. 5201-5210 (2021). (Supplementary cover article)

10. C. Y. Zhang, S. K. Yao, C. Xu, Y. N. Chang, Y. B. Zong, K. Zhang, X. Z. Zhang, L. J. Zhang, C. Y. Chen, Y. L. Zhao, H. D. Jiang^*, X. Gao^*, Y. L. Wang^*, “3D imaging and quantification of the integrin at a single-cell base on a multisignal nanoprobe and synchrotron radiation soft X-ray tomography microscopy”, Anal. Chem. 93, 1237-1241 (2021).

11. C. Jung, Y. Ihm, D. H. Cho, H. Lee, D. Nam, S. Kim, I. T. Eom, J. Park, C. Kim, Y. Kim, J. D. Fan, N. J. Ji, J. R Morris, S. Owada, K. Tono, J. H. Shim, H. D. Jiang, M. Yabashi, T. Ishikawa, D. Y. Noh, C. Y. Song, “Inducing thermodynamically blocked atomic ordering via strongly driven nonequilibrium kinetics”, Science Advances 7, eabj8552 (2021).

12. L. Gao, Y. Zhang, L. N, Zhao, W. C. Niu, Y. H. Tang, F. P. Gao, P. Cai, Q. Yuan, X. Y. Wang, H. D. Jiang, X. Y. Gao, “An artificial metalloenzyme for catalytic cancer-specific DNA cleavage and operando imaging”, Science Advances 6, eabb1421 (2020).

13. A. Rana^#, J. H. Zhang^#, M. Pham, A. Yuan, Y. H. Lo, H. D. Jiang, S. Osher, J. Miao, “Potential of attosecond coherent diffractive imaging”, Phys. Rev. Lett. 125, 086101 (2020). (Highlighted by Science 369, 1337, 2020)

14. C. Y. Zhang, L. Gao, Q. Yuan, L. N. Zhao, W. C. Niu, P. J. Cai, J. J. Li, X. Han, Z. He, F. P. Gao, Y. L. Wang, H. D. Jiang, Z. F. Chai, X. Y. Gao, “Is GSH Chelated Pt Molecule Inactive in Anti‐Cancer Treatment? A Case Study of Pt₆GS₄”, Small 16, e2002044 (2020).

15. N. Q. Gong, X. W. Ma, X. Ye, Q. F. Zhou, X. Chen, X. L. Tan, S. K. Yao, S. D. Huo, T. B. Zhang, S. Chen, X. Teng, X. X. Hu, J. Yu, Y. L. Gan, H. D. Jiang, J. Li, X. J. Liang, “Carbon-dot-supported atomically dispersed gold as a mitochondrial oxidative stress amplifier for cancer treatment”, Nature Nanotechnology 14, 379-387 (2019).

16. Z. Q. Li, P. F. Zhu, J. M. Ding, N. J. Ji, Y. Chen, Z. Y. Wang, X. L Duan^*, H. D. Jiang^*, “Increased concentration of Yb³⁺ and high crystal field strength in RbTiOPO₄:Ta single crystal with optimized growth”, Crystal Growth & Design 19, 7143-7152 (2019).

17. Z. B. Sun, J. D. Fan, H. Y. Li, H. J. Liu, D. W. Nam, C. Kim, Y. H. Kim, Y. B. Han, J. H. Zhang, S. K. Yao, J. H. Park,S. N. Kim, K. Tono, M. Yabashi, T. Ishikawa, C. Y. Song, C. H. Fan, H. D. Jiang^*, “Necessary Experimental Conditions for Single-Shot Diffraction Imaging of DNA-Based Structures with X-ray Free-Electron Lasers”, ACS Nano 12, 7509-7518 (2018).

18. S. K. Yao, J. D. Fan, Z. Y. Chen, Y. B. Zong, J. H. Zhang, Z. B. Sun, L. J. Zhang, R. Z. Tai, Z. Liu, C. Y. Chen, H. D. Jiang^*, “Three-dimensional ultrastructural imaging reveals the nanoscale architecture of mammalian cells”, IUCrJ 5, 141-149 (2018). (Cover article)

19. R. Mani, S. K. Gupta, P. S. Ghosh, H. D. Jiang^*, “Yellow Emission from Low Coordination Site of Sr₂SiO₄:Eu²⁺, Ce³⁺: Influence of Lanthanide Dopants on the Electron Density and Crystallinity in Crystal Site Engineering Approach”, Chemistry - A European Journal 24, 16149-16159 (2018). 

20. B. J. Ma, Y. Wu, S. Zhang, S. C. Wang, J. C. Qiu, L. L. Zhao, D. D. Guo, J. Z. Duan, Y. H. Sang, L. L. Li, H. D. Jiang^*, H. Liu^*, “Terbium-Aspartic Acid Nanocrystals with Chirality-Dependent Tunable Fluorescent Properties”, ACS Nano 11, 1973-1981 (2017).

21. B. J. Ma, S. Zhang, R. Y. Liu, J. C. Qiu, L. L. Zhao, S. C. Wang, J. Li, Y. H. Sang, H. D. Jiang^*, H. Liu^*, “Prolonged fluorescence lifetime of carbon quantum dots by combining with hydroxyapatite nanorods for bio-applications”, Nanoscale 9, 2162-2171 (2017).

22. Y. B. Zong, S. K. Yao, G. W. Crawford, H. Fang, J. F. Lang, J. D. Fan, Z. B. Sun, Y. Liu, J. H. Zhang, X. L. Duan, G. Z. Zhou, T. Q. Xiao, F. S. Luan, Q. Wang, X. X. Chen^*, H. D. Jiang^*, “Selection for oil content during soybean domestication revealed by x-ray tomography of ancient beans”, Scientific Reports 7, 43595 (2017).

23. Y. B. Zong, S. K. Yao, J. F. Lang, X. X. Chen, J. D. Fan, Z. B. Sun, X. L. Duan, N. N. Li, H. Fang, G. Z. Zhou, T. Q. Xiao, A. G. Li, H. D. Jiang^*, “Structural and compositional analysis of a casting mold sherd from ancient China”, PLoS ONE 12, 0-e0174057 (2017).

24. J. D. Fan, Z. B. Sun, Y. L. Wang, J. Park, S. Kim, M. Gallagher-Jones, Y. Kim, C. Song, S. K. Yao, J. Zhang, J. H. Zhang, X. L. Duan, K. Tono, M. Yabashi, T. Ishikawa, C. H. Fan, Y. L. Zhao, Z. F. Chai, X. Y. Gao^*, T. Earnest, H. D. Jiang^*, “Single-pulse enhanced coherent diffraction imaging of bacteria with an X-ray free-electron laser”, Scientific Reports 6, 34008 (2016).

25. S. K. Yao, J. D. Fan, Y. B. Zong, Y. He, G.Z. Zhou, Z. B. Sun, J. H. Zhang, Q. J. Huang, T. Q. Xiao, H. D. Jiang^*, “Equally sloped X-ray microtomography of living insects with low radiation dose and improved resolution capability”, Applied Physics Letters 108, 123702 (2016).

26. J. H. Li, J. C. Qiu, W. B. Guo, S. Wang, B. J. Ma, X. N. Mou, Mi. Tanes, H. D. Jiang^*, H. Liu^*, “Cellular internalization of LiNbO₃ nanocrystals for second harmonic imaging and the effects on stem cell differentiation”, Nanoscale 8, 7416-7422 (2016).

27. H. D. Jiang, “Cryo-coherent diffractive imaging of biological samples with X-ray free-electron lasers”, Acta Cryst. A72, 177–178 (2016).

28. J. D. Fan, Z. B. Sun, J. Zhang, Q. J. Huang, S. k. Yao, Y. b. Zong, Y. Kohmura, T. Ishikawa, H. Liu, H. D. Jiang^*, Quantitative Imaging of Single Unstained Magnetotactic Bacteria by Coherent X-ray Diffraction Microscopy, Analytical Chemistry 87, 5849-5853 (2015).

29. J. D. Fan, Y. Zhang, N. J. Ji, X. L. Duan, H. liu, J. Y. Wang, H. D. Jiang^*, Hierarchical structures of self-assembled hybrid calcium carbonate: nucleation kinetic studies on biomineralization, CrystEngComm. 17, 5372-5376, (2015). (Inside front cover article)

30. J. Zhang, J. D. Fan, J. H. Zhang, Z. B. Sun, Q. J. Huang, H. D. Jiang^*, “Three-dimensional coherent diffraction imaging of Mie-scattering spheres by laser single-orientation measurement”, Chin. Phys. B 24, 094201 (2015). (Suggested by editors)

31. H. D. Li, Y. H. Sang, S. Chang, X. Huang, Y. Zhang, R. S. Yang,H. D. Jiang, H. Liu, Z. L. Wang, Enhanced Ferroelectric-Nanocrystal-Based Hybrid Photocatalysis by Ultrasonic-Wave-Generated Piezophototronic Effect, Nano letters. 15 (4), 2372-2379 (2015).

32. R. Xu, H. D. Jiang, C. Song, J. A. Rodriguez, Z. Huang, C.-C. Chen, D. Nam, J. Park, M. Gallagher-Jones, S. Kim, S. Kim, A. Suzuki, Y. Takayama, T. Oroguchi, Y. Takahashi, J. Fan, Y. Zou, T. Hatsui, Y. Inubushi, T. Kameshima, K. Yonekura, K. Tono, T. Togashi, T. Sato, M. Yamamoto, M. Nakasako, M. Yabashi, T. Ishikawa and J. Miao, Single-shot three-dimensional structure determination of nanocrystals with femtosecond X-ray free-electron laser pulses, Nature Commun. 5, 4061 (2014).

33. H. D. Jiang, R. Xu, C.-C. Chen, W. Yang, J. Fan, X. Tao, C. Song, Y. Kohmura, T. Xiao, Y. Wang, Y. Fei, T. Ishikawa, W. L. Mao, and J. Miao, “Three-dimensional coherent x-ray diffraction imaging of molten iron in mantle olivine at nanoscale resolution”, Phys. Rev. Lett., 110, 205501 (2013).

34. J. Tian, Y. Sang, G. Yu, H. D. Jiang, X. Mu, H. Liu, “A Bi₂WO₆‐based hybrid photocatalyst with broad spectrum photocatalytic properties under UV, visible, and near-infrared irradiation”, Advanced Materials 25, 5075-5080 (2013).

35. H. D. Jiang, C. Song, C. C. Chen, R. Xu, K. Raines, B. Fahimian, C. H. Lu, T. K. Lee, A. Nakashima, J. Urano, T. Ishikawa, F. Tamanoi, J. Miao “Quantitative 3D imaging of whole, unstained cells at a resolution of 50 - 60 nm by X-ray diffraction microscopy”, Proc. Natl. Acad. Sci. USA, 107, 11234-11239 (2010).

36. K. S. Raines, S. Salha, R. Sandberg, H. D. Jiang, J. A. Rodríguez, B. P. Fahimian1, H. C. Kapteyn, J. Du, J. Miao “Ankylography: three-dimensional structure determination from a single view”, Nature 463, 214-217 (2010). (Highlighted byNature Methods7, 96, 2010)

37. H. D. Jiang, D. Johnson,C. Song, B. Amirbekian, Y. Kohmura, Y. Nihino, Y. Takahashi,T. Ishikawa, J. Miao “Nanoscale Imaging of Mineral Crystals inside Biological Composite Materials Using X-ray Diffraction Microscopy”, Phys. Rev. Lett. 100, 038103 (2008).

38. C. Song, H. D. Jiang, A. Mancuso, B. Amirbekian, L. Peng, R. Sun, S. S. Shah, Z. H. Zhou, T. Ishikawa, J. Miao “Quantitative Imaging of Single, Unstained Viruses with Coherent X Rays”, Phys. Rev. Lett. 101, 158101 (2008).

39. C. Song, R. Bergstrom, D. Ramunno-Johnson, H. D. Jiang, D. Paterson, M. D. de Jonge, I. McNulty, J. Lee, K. Wang, J. Miao “Nanoscale Imaging of Buried Structures with Elemental Specificity Using Resonant X-ray Diffraction Microscopy”, Phys. Rev. Lett. 100, 025504 (2008). (Highlighted byNature Nanotechnology3, 126, 2010)

40. H. D. Jiang, X. Y. Liu, G. Zhang, Y. Li “Kinetics and template nucleation of self-assembled hydroxyapatite nanocrystallites by chondroitin sulfate,” J. Biol. Chem. 280, 42061-42066 (2005).

41. H. D. Jiang, X. Y. Liu “Principles of mimicking and engineering the self-organized structure of hard tissues,”J. Biol. Chem. 279 (40), 41286-41293 (2004).

本组成员